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Musculoskeletal & Anti-Inflammatory Effects GLP-1 receptors are present in: Chondrocytes Synovial tissues Macrophages Potential benefits include: Reduced inflammatory cytokines NF-B inhibition Reduced cartilage degradation Improvement in osteoarthritis inflammation The anti-inflammatory role of GLP-1 may become clinically important in rheumatologic and degenerative diseases

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Recent signals underscore this shift: Eli Lilly became the first pharmaceutical company to surpass a $1 trillion market capitalization [1] buoyed by global demand for obesity medications

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